OsCorp Industries (The Spectacular Spider-Man)

Oscorp is the leading chemical manufacturing firm (which also had research divisions that dealt in other areas) that is based in New York City and was originally founded and owned by the ruthless businessman, inventor, and gifted chemist named Norman Osborn.

At some point, Norman came across a chemical formula with the intention of using it to increase a person's intelligence and physical strength. Osborn tried to recreate the chemical (secretly) and used small doses of it. The formula indeed increased his intelligence and strength, but it also drove him insane. He created a Halloween-like costume for himself which he colored green after the solution and named himself the Green Goblin for which his major objective was to become the reigning crime boss in New York and to kill Spider-Man.