Man-Spider

Man Spider is the mutated form of Spider-Man.

Biography
When Spider-Man's body began to mutate further he sought out the help of Dr. Mariah Crawford who gave him what she believed to be a cure. However, it accelerated the changes and he grew four extra arms, for a total of six limbs. Peter still felt he needed to capture Michael Morbius, and then the Punisher arrived to take Spider-Man down believing the media. Spider-Man eventually mutated further into a creature dubbed "Man Spider." Man Spider could shoot acid from it's mouth and webbing from every limb without webshooters. Man Spider had feelings from Peter but did not seem to possess any of Peter's memories, and vice-versa. Man Spider continued searching out Morbius while fighting the Punisher. Dr. Crawford then asked out her boyfriend Kraven the Hunter to find Man Spider, who also tangled with Punisher. Punisher was eventually captured by Man Spider and taken to the World Trade Center parking garage. Kraven followed the mutated hero there and was able to administer another cure, this time reversing the effects. The nightmare was not over however. Spider-Man would have to continually see Dr. Curt Connors to stop the mutation, sometimes the arms would begin to grow again.

Alternate Version
Another version has just gotten to the point where he grew the extra arms. But instead of seeing them as a bother, this Spider-Man adapted and made a costume to cover the extra arms and got additional web shooters. When he went to fight Spider-Carnage he further mutated into Man Spider and attacked the other Spider-Men, which forced the Beyonder to teleport him away.

Background
Man Spider was voiced by Jim Cummings who also voiced Shocker, Chameleon, "Slash" Curtis, "Bull" Donovan, "Skink" Lomas, President Bill Clinton, MODOK, E.L.F., Grey Gargoyle, Century, and Absorbing Man in the MAU; and on.

In the comics, Spider-Man did grow four extra arms but did not mutate into a large spider.