Fantastic Four (Yost Universe)

The Fantastic Four is a group of superheroes consisting of four members imbued by cosmic radiation. They often assist the Avengers in various battles against villians and are often fought by Doctor Doom.

The Man Who Stole Tomorrow
Only a picture of them were seen on the wall since Thor and Wasp came along with Ant-Man to drop off Blizzard to Number 42.

The Private War of Doctor Doom
The Thing and Human Torch are seen going to the Avengers Mansion and surprise Hawkeye saying "Is it 7:00 already" since they agreed they were going to play cards. However Hulk attacks the Thing due to his strong dislike of him (though reasons unknown). During this Iron Man and Wasp go to the Baxter Building to visit Mr. Fantastic and Invisible Woman. But while playing cards (in which the Hulk attacked the Thing for beating him) they are attacked by Doombots as well as Mr. Fantastic, Iron Man, Wasp and Invisible Woman. While creating Bombs at both loctations to distract the others Wasp and Invisible Woman are taken. Then both teams go to defeat Doom but when they infiltrate the base Doom lets them go saying "do you not see what is happening here". Later on they try to figure out what Doom wanted at the mansion while Doom is at his base and discovers that The Invisible Woman is a Skrullposing as the real one.

Alone Against A.I.M.
They are mentioned by Maria Hill among other heroes (Spider-Man, X-Men) that they want to join S.H.I.E.L.D.under the Superhuman Regristration Act in her meeting with Iron Man.