Miriam

A vampire Queen obsessed with populating the world with Vampires, Mirium is the Mother of Blade, The Vampire Hunter. She is also the arch-nemesis of Supernatural.

After discovering that the Neogenic Recombinator could create vampires she flew to New York to create her own army before Spider-Man, Morbius, Blade and Black Cat stopped her. After which she fled, with Morbius, Blade and Black Cat following her through Europe to stop her turning anyone else.